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appA/1 [2020-04-17 16:52:21]
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appA/1 [2020-04-17 16:52:21]

oligopeptide ABC transporter, inactive pseudogene in strain 168
locus
BSU_11381
pI
0.00
mw
0.00 kDa
protein length
154 aa Sequence Blast
gene length
465 bp Sequence Blast
function
unknown
product
oligopeptide ABC transporter
essential
no
synonyms
Outlinks
KEGGBsubCycExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.3|Uptake of peptides]
  • [category|SW 6|Groups of genes] → [category|SW 6.10|Pseudogenes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,213,537 → 1,214,001

    The protein

    Protein family

  • [SW|bacterial solute-binding protein 5 family] (according to UniProt)

    • [SW|Localization]

  • attached to the cell membrane (via [protein|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|AppB]-[protein|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|AppC]) [Pubmed|10092453]

    • Expression and Regulation

    Operons

    genes
    [gene|325BCDCAB4003204294229B7F9F0A5F353D72B54|appD]-[gene|B88A88B4792FFFF4E1609B1FC91AAE6DBA339044|appF]-[gene|DD2C5F549759447FF1C30E5B43BCB74CE4320EF3|appA/1]-[gene|082D2012ABE3671F62211F77ED501849BF77B4EF|appA/2]-[gene|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|appB]-[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]
    description
    [Pubmed|7997159]

    regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: activation, [Pubmed|25755103], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon]
  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [pubmed|12618455] [pubmed|18083814], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]
  • [protein|F7FD94CE7AB290FBFD3A9B88F204961668F9B42C|ScoC]: repression, [Pubmed|10383984], in [regulon|F7FD94CE7AB290FBFD3A9B88F204961668F9B42C|ScoC regulon]

    • regulation

  • repressed by [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY] [Pubmed|12618455]
    • view in new tab

    Biological materials

    Mutant

  • GP2100 (D(''[gene|325BCDCAB4003204294229B7F9F0A5F353D72B54|appD]-[gene|B88A88B4792FFFF4E1609B1FC91AAE6DBA339044|appF]-[gene|082D2012ABE3671F62211F77ED501849BF77B4EF|appA/2]-[gene|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|appB]-[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]'')::''spc''), available in [SW|Jörg Stülke]'s lab
  • BKE11381 (Δ[gene|DD2C5F549759447FF1C30E5B43BCB74CE4320EF3|appA/1]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11381 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAGATATTCCCCCTCTT, downstream forward: _UP4_ATGCTGAAATCCGTAGAAAA
  • BKK11381 (Δ[gene|DD2C5F549759447FF1C30E5B43BCB74CE4320EF3|appA/1]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11381 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAGATATTCCCCCTCTT, downstream forward: _UP4_ATGCTGAAATCCGTAGAAAA

    • References

  • 12618455,7997159,10092453,10383984,12618455,25755103